Nail-Bed Squamous Cell Carcinoma (SCC)Digital SCC is a malignant tumor that originates in the nail-bed epithelium. Most dogs with SCC of the digit are examined because of a sore toe. Limping, swelling, bleeding/discharge, ulceration, and breaking or splitting of nails are also common complaints. SCC tumors in many dogs were preceded by chronic nail-bed infections. Black, large breed dogs such as Standard Poodles, Giant Schnauzers and Bouviers appear to be predisposed. In these breeds, multiple digits may be involved over a course of two to four years. Each toe affected is a primary tumor, and not metastases from another digit. Squamous Cell Carcinoma of the digit is locally aggressive, and "lysis" (erosion and deterioration of bone) is evident on X-rays about 80% of the time. Amputation of the digit is necessary to prevent SCC from spreading to adjacent lymph nodes and major organs. It is recommended that more than the P3 (tip of the toe) be amputated. A P1 or even a P2 amputation, but always more than the P3.Average age at the onset of SCC is nine, but Standard Poodles as young as four have been reported. Diagnosis is confirmed by histopathology of the affected digit. Additional InformationReferencesDr. Steven Kruth DVM, ACVIM Dr. Joke Brouwers DVM Dr. Robert Leonard DVM Clinical Signs, Diagnosis and Treatment of Specific Cancers in Dogs
and Cats. To enter a Standard Poodle with Digital SCC into the registry, please contact:
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